Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)

  title={Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)},
  author={P. Olsvik and K. Lie and E. Mykkeltvedt and O. Samuelsen and K. Petersen and A. Stavrum and B. T. Lunestad},
  journal={BMC Pharmacology},
  pages={16 - 16}
  • P. Olsvik, K. Lie, +4 authors B. T. Lunestad
  • Published 2008
  • Biology, Medicine
  • BMC Pharmacology
  • BackgroundEmamectin benzoate (EB) is a dominating pharmaceutical drug used for the treatment and control of infections by sea lice (Lepeophtheirus salmonis) on Atlantic salmon (Salmo salar L). Fish with an initial mean weight of 132 g were experimentally medicated by a standard seven-day EB treatment, and the concentrations of drug in liver, muscle and skin were examined. To investigate how EB affects Atlantic salmon transcription in liver, tissues were assessed by microarray and qPCR at 7, 14… CONTINUE READING
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