Pharmacokinetics and toxic effects of lithium chloride after intravenous adminstration in conscious horses.


OBJECTIVE To determine the pharmacokinetics and toxic effects associated with IV administration of lithium chloride (LiCl) to conscious healthy horses. ANIMALS 6 healthy Standardbred horses. PROCEDURE Twenty 3-mmol boluses of LiCl (0.15 mmol/L) were injected IV at 3-minute intervals (total dose, 60 mmol) during a 1-hour period. Blood samples for… (More)