Pharmacokinetics and tolerability of meloxicam after i.m. administration.

  title={Pharmacokinetics and tolerability of meloxicam after i.m. administration.},
  author={H. H. Narjes and Dietrich Tuerck and Ulrike Busch and Gerhard Heinzel and Gerhard Nehmiz},
  journal={British journal of clinical pharmacology},
  volume={41 2},
1. The pharmacokinetics and tolerability of a new nonsteroidal anti-inflammatory drug (NSAID), meloxicam, administered i.m., were investigated in two studies conducted in healthy male volunteers. Study 1 was an open, placebo-controlled design in which 32 volunteers were randomized to a single ascending i.m. dose of meloxicam (5, 10, 20, and 30 mg) or placebo. Study 2 had an open, randomized two way crossover design in which 12 volunteers received single i.m. and i.v. doses of meloxicam (15 mg… CONTINUE READING

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