Pharmacokinetics and suction blister fluid penetration of a semisynthetic injectable streptogramin RP 59500 (RP 57669/ RP 54476)

@article{Bernard1994PharmacokineticsAS,
  title={Pharmacokinetics and suction blister fluid penetration of a semisynthetic injectable streptogramin RP 59500 (RP 57669/ RP 54476)},
  author={Estrada Bernard and Maurice Bensoussan and F. Bensoussan and Sylvie Etienne and Isabelle Cazenave and E. Carsenti-Etesse and Y. Le Roux and Guy Montay and Pierre Dellamonica},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={1994},
  volume={13},
  pages={768-771}
}
RP 59500 is a new semisynthetic injectable streptogramin with excellent activity against most gram-positive bacteria. In order to assess its potential for the treatment of tissue infections, the pharmacokinetics and penetration into suction blister fluid were studied in a pilot phase I study in six male volunteers following a single infusion of 12 mg/kg… CONTINUE READING