Pharmacokinetics and safety study of posaconazole intravenous solution administered peripherally to healthy subjects.

Abstract

This study evaluated the safety, tolerability, and pharmacokinetics of a posaconazole i.v. (intravenous) solution. This was a single-center, 2-part, randomized, rising single- and multiple-dose study in healthy adults. In part 1, subjects received 0 (vehicle), 50, 100, 200, 250, or 300 mg posaconazole in a single dose i.v. by 30-min peripheral infusion (6… (More)
DOI: 10.1128/AAC.04223-14

Topics

Cite this paper

@article{Kersemaekers2015PharmacokineticsAS, title={Pharmacokinetics and safety study of posaconazole intravenous solution administered peripherally to healthy subjects.}, author={Wendy M Kersemaekers and Thijs van Iersel and Ulla Nassander and Edward O'Mara and Hetty Waskin and Mar{\'i}a Elena C{\'a}ceres and Marlou L P S van Iersel}, journal={Antimicrobial agents and chemotherapy}, year={2015}, volume={59 2}, pages={1246-51} }