Pharmacokinetics and safety of intravenous ceftolozane-tazobactam in healthy adult subjects following single and multiple ascending doses.

Abstract

The pharmacokinetics and safety of ceftolozane, a novel cephalosporin, and tazobactam, a β-lactamase inhibitor, alone and in combination as a 2:1 ratio in single doses of up to 2,000 and 1,000 mg of ceftolozane and tazobactam, respectively, and multiple doses of up to 3,000 and 1,500 mg of ceftolozane and tazobactam, respectively, per day were evaluated in… (More)
DOI: 10.1128/AAC.06349-11

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Cite this paper

@article{Miller2012PharmacokineticsAS, title={Pharmacokinetics and safety of intravenous ceftolozane-tazobactam in healthy adult subjects following single and multiple ascending doses.}, author={Benjamin Miller and Ellie Hershberger and David P Benziger and Mymy Trinh and Ian M. Friedland}, journal={Antimicrobial agents and chemotherapy}, year={2012}, volume={56 6}, pages={3086-91} }