Corpus ID: 2091704

Pharmacokinetics and plasma protein binding (in vitro) of oxytetracycline in buffalo (Bubalus bubalis).

@article{Varma1983PharmacokineticsAP,
  title={Pharmacokinetics and plasma protein binding (in vitro) of oxytetracycline in buffalo (Bubalus bubalis).},
  author={K. M. Varma and B. Saint Paul},
  journal={American journal of veterinary research},
  year={1983},
  volume={44 3},
  pages={
          497-9
        }
}
  • K. M. Varma, B. Saint Paul
  • Published in
    American journal of…
    1983
  • Medicine
  • The pharmacokinetics of oxytetracycline given in a single dose (22 mg/kg) either IV or IM was studied in 4 female buffalo calves. The half-life (t1/2) after IV administration varied between 169.02 and 216.56 minutes and that after IM administration, between 630 and 990 minutes. The drug was distributed well in the body after IM administration (Vdarea 1.18 to 2.15 L/kg). The total body clearances varied between 1.02 and 1.45 and between 1.17 and 1.49 ml/kg/min after the IV and the Im dosings… CONTINUE READING

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