Pharmacokinetics and pharmacodynamics of estramustine phosphate.

  title={Pharmacokinetics and pharmacodynamics of estramustine phosphate.},
  author={A. Tommy Bergenheim and Roger Henriksson},
  journal={Clinical pharmacokinetics},
  volume={34 2},
Estramustine phosphate (estramustine phosphate sodium), a carbamate ester combining 17 beta-estradiol and nor-nitrogen mustard, is a cytotoxic drug used in the treatment of advanced prostatic carcinoma. Because of the radiosensitising effect of this drug there has been a recent increase in interest concerning estramustine phosphate and its clinical use. It has also been found that the early recommendations of drug administration together with food or milk were inappropriate, since calcium… CONTINUE READING
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