Pharmacokinetics and pharmacodynamics of anastrozole in pubertal boys with recent-onset gynecomastia.

Abstract

CONTEXT Use of aromatase inhibitors to suppress estrogen production is being actively investigated in a variety of experimental conditions in both females and males. Anastrozole (Arimidex) is a potent and selective reversible inhibitor of the aromatase enzyme in females. OBJECTIVE Our objective was to characterize the pharmacokinetics (PK) and… (More)
DOI: 10.1210/jc.2008-2527

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