Pharmacokinetics and effects of propranolol in terminal uraemic patients and in patients undergoing regular dialysis treatment.

@article{Bianchetti1976PharmacokineticsAE,
  title={Pharmacokinetics and effects of propranolol in terminal uraemic patients and in patients undergoing regular dialysis treatment.},
  author={Gabrio Bianchetti and Giorgio Graziani and Diego Brancaccio and Alberto Morganti and Gastonea Leonetti and Marcello Manfrin and Roberto Sega and Roberto Gomeni and Claudio Ponticelli and Paolo Lucio Morselli},
  journal={Clinical pharmacokinetics},
  year={1976},
  volume={1 5},
  pages={
          373-84
        }
}
Propranolol blood and plasma levels were measured after a single oral dose of 40 mg in patients with chronic renal failure, in patients undergoing regular dialysis treatment, and in healthy volunteers. Peak levels were observed in all cases within 1.5 to 3 hours. However, peak blood and plasma concentrations of propranolol in the chronic renal failure group were 2- to 3-fold higher (161 +/- 41 ng/ml) than those observed in the dialysis patients (47 +/- 9 ng/ml) and in the healthy volunteers (26… CONTINUE READING
Highly Cited
This paper has 35 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 citations