Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats.

@article{Albarellos2012PharmacokineticsAB,
  title={Pharmacokinetics and bone tissue concentrations of lincomycin following intravenous and intramuscular administrations to cats.},
  author={Gabriela A Albarellos and Laura Montoya and Graciela A A Denamiel and Marilia Mattar de Amo{\^e}do Campos Velo and M Fabiana Landoni},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2012},
  volume={35 6},
  pages={534-40}
}
The pharmacokinetic properties and bone concentrations of lincomycin in cats after single intravenous and intramuscular administrations at a dosage rate of 10 mg/kg were investigated. Lincomycin minimum inhibitory concentration (MIC) for some gram-positive strains isolated from clinical cases was determined. Serum lincomycin disposition was best-fitted to a bicompartmental and a monocompartmental open models with first-order elimination after intravenous and intramuscular dosing, respectively… CONTINUE READING

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