Pharmacokinetics and blister fluid penetration of brodimoprim in adults.

@article{Novelli1993PharmacokineticsAB,
  title={Pharmacokinetics and blister fluid penetration of brodimoprim in adults.},
  author={Andrea Novelli and Teresita Mazzei and E. Zarba Meli and Maria Iris Cassetta and Stefania Fallani and Piero Periti},
  journal={Journal of chemotherapy},
  year={1993},
  volume={5 6},
  pages={494-8}
}
We investigated the pharmacokinetic properties of brodimoprim (B), a new diaminopyrimidine, including its penetration into suction blister fluid (SBF) after a single or multiple oral dose in 15 patients with a mean age of 61.5 +/- 9.3 yrs, suffering from respiratory tract infections with normal renal and hepatic function. Patients were divided into 3 groups… CONTINUE READING