Pharmacokinetics and bioequivalence of 20 mg omeprazole capsule in 24 healthy Korean male volunteers.

@article{Rhim2009PharmacokineticsAB,
  title={Pharmacokinetics and bioequivalence of 20 mg omeprazole capsule in 24 healthy Korean male volunteers.},
  author={S. H. Rhim and Jong-Ho Park and Ye-Soo Park and M Lee and K-G Hwang and Y-S Kim and Leslie M. Shaw and Yun-Sang Lee and J S Kang},
  journal={International journal of clinical pharmacology and therapeutics},
  year={2009},
  volume={47 1},
  pages={23-9}
}
OBJECTIVE A randomized, two-way, crossover bioequivalence study in 24 healthy Korean male volunteers was conducted to compare bioequivalence of two brands of 20 mg omeprazole capsules, Hutex omeprazole (Hutex Pharm Co. Korea) as a test and Yuhan Losec (Yuhan Co. Ltd., Korea) as a reference drug. VOLUNTEERS AND METHODS Subjects were administered single dosage of 1 capsule of 20 mg of each formulation with 240 ml of water after 10 hs overnight fasting on 2 treatment days separated by one-week… CONTINUE READING