Pharmacokinetics and Pharmacodynamics in Clinical Use of Scopolamine

@article{Renner2005PharmacokineticsAP,
  title={Pharmacokinetics and Pharmacodynamics in Clinical Use of Scopolamine},
  author={Ulf D Renner and Reinhard Oertel and Wilhelm Kirch},
  journal={Therapeutic Drug Monitoring},
  year={2005},
  volume={27},
  pages={655-665}
}
The alkaloid L-(−)-scopolamine [L-(−)-hyoscine] competitively inhibits muscarinic receptors for acetylcholine and acts as a nonselective muscarinic antagonist, producing both peripheral antimuscarinic properties and central sedative, antiemetic, and amnestic effects. The parasympatholytic scopolamine, structurally very similar to atropine (racemate of hyoscyamine), is used in conditions requiring decreased parasympathetic activity, primarily for its effect on the eye, gastrointestinal tract… 
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