Pharmacokinetics and Clinical Effectiveness of Methylphenidate

@article{Kimko1999PharmacokineticsAC,
  title={Pharmacokinetics and Clinical Effectiveness of Methylphenidate},
  author={H. Kimko and J. Cross and D. Abernethy},
  journal={Clinical Pharmacokinetics},
  year={1999},
  volume={37},
  pages={457-470}
}
Methylphenidate is prescribed for over 90% of children in the US diagnosed as having attention-deficit hyperactivity disorder (ADHD). Although ADHD has been widely studied, the use of methylphenidate in ADHD still poses a number of unresolved questions, including its pharmacodynamic characteristics (drug concentration-effect relationship) and the effect of long term treatment on the patient’s psychopathology later in life. The objective of this review is to provide an analysis of the… Expand
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