Pharmacokinetics and Bioavailability of Florfenicol Following Intravenous, Intramuscular and Oral Administrations in Rabbits

@article{ElAty2004PharmacokineticsAB,
  title={Pharmacokinetics and Bioavailability of Florfenicol Following Intravenous, Intramuscular and Oral Administrations in Rabbits},
  author={A. M. Abd El-Aty and Ayman M Goudah and K. Abo El-Sooud and H. Y. El-zorba and Minoru Shimoda and H.-H. Zhou},
  journal={Veterinary Research Communications},
  year={2004},
  volume={28},
  pages={515-524}
}
This study examined the disposition kinetics and bioavailability of florfenicol after intravenous (i.v.), intramuscular (i.m.) and oral administration to rabbits at a dose of 30 mg/kg BW. Serial blood samples were collected through an indwelling catheter intermittently for 24 h for various routes. Plasma antibacterial concentrations were determined using a microbiological assay method withBacillus subtilis ATCC 6633 as a reference organism. Plasma concentration–time data generated in the… CONTINUE READING
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