Pharmacokinetics: metabolism and renal excretion of quinolones in man

Abstract

The quinolones are relatively poorly absorbed from the gastrointestinal tract. The elimination proceeds mainly by renal excretion. The half-life of elimination depends on the molecular structure and varies between 2 and 10 h. Impaired kidney function is expected to increase the half-life of elimination. though this effect is not always observed. Since the 4… (More)
DOI: 10.1007/BF01975476

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