Pharmacokinetics, tissue distribution, metabolism, and excretion of ginsenoside Rg1 in rats.

The pharmacokinetics, tissue distribution, metabolism, and excretion of ginsenosides Rg(1) were studied in Wistar rats, by measuring the concentrations of Rg(1) and its metabolites in the blood, tissues, bile, urine, and feces after dosing. After intravenous (i.v.) administration, the elimination half-lives of Rg(1) and its metabolites were 1.82, 5.87, and… CONTINUE READING