Pharmacokinetics, efficacy, and safety of analgesia with a focus on tramadol HCl.

@article{Gibson1996PharmacokineticsEA,
  title={Pharmacokinetics, efficacy, and safety of analgesia with a focus on tramadol HCl.},
  author={T. P. Gibson},
  journal={The American journal of medicine},
  year={1996},
  volume={101 1A},
  pages={47S-53S}
}
  • T. P. Gibson
  • Published 1996 in The American journal of medicine
Chronic pain remains a problem because it is often misdiagnosed and undertreated. Adverse effects and safety concerns associated with many analgesics have limited the use of these agents and contributed to the undertreatment of pain. With regard to the pharmacologic agents most commonly used to manage pain, centrally acting analgesics (e.g., morphine, codeine) are associated with respiratory depression, tolerance, and dependence, and most nonsteroidal anti-inflammatory drugs (NSAIDs) produce… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…