Pharmacokinetics, Organ Toxicity and Antitumor Activity of Docetaxel Loaded in Folate Targeted Cholesterol Based Micelles.

Abstract

BACKGROUND To overcome insufficient concentration of chemotherapeutic drugs at tumor site and severe side effects in non-targeted tissues which limit their use targeting their overexpressed receptors represent a promising approach for cancer therapy. METHODS The antitumor activity of docetaxel (DTX) loaded in folate targeted Synpronic F127- Cholesterol… (More)

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Cite this paper

@article{Taymouri2016PharmacokineticsOT, title={Pharmacokinetics, Organ Toxicity and Antitumor Activity of Docetaxel Loaded in Folate Targeted Cholesterol Based Micelles.}, author={Somayeh Taymouri and Jaleh Varshosaz and Farshid Hassanzadeh and Shaghayegh Haghjoo Javanmard and Parvin Mahzouni}, journal={Current drug delivery}, year={2016}, volume={13 4}, pages={545-56} }