Pharmacokinetic study of carbamazepine and its carbamazepine 10,11-epoxide metabolite in a group of female epileptic patients under chronic treatment.

@article{Moreno2004PharmacokineticSO,
  title={Pharmacokinetic study of carbamazepine and its carbamazepine 10,11-epoxide metabolite in a group of female epileptic patients under chronic treatment.},
  author={J. Santiago Moreno and Aurora Belmont and Orlando Jaimes and Jose A. Santos and Guadalupe L{\'o}pez and Maria de Lourdes Garcia Campos and Octavio Amancio and Patricia P{\'e}rez and Gerardo Heinze},
  journal={Archives of medical research},
  year={2004},
  volume={35 2},
  pages={168-71}
}
BACKGROUND Although epileptic crises are equally frequent in women and men, several factors cause female epileptics to present a series of gender-specific problems. To date, few studies have been published on the kinetics of carbamazepine (CBZ) and carbamazepine 10,11-epoxide (CBZ-E) active metabolite in a Mexican population, and no information for epileptic women of reproductive age is available. The aim of the present work was to study the pharmacokinetic behavior of this group of women… CONTINUE READING

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