Pharmacokinetic study of S-1 in patients in whom inulin clearance was measured.

@article{Ando2012PharmacokineticSO,
  title={Pharmacokinetic study of S-1 in patients in whom inulin clearance was measured.},
  author={Yuichi Ando and Kenji Kawada and Megumi Inada and Sachi Morita and Ayako Mitsuma and Yoshinari Yasuda and Mariko Hiramatsu and Yasushi Fujimoto and Ken-Ichi Fujita},
  journal={Oncology},
  year={2012},
  volume={83 1},
  pages={38-44}
}
OBJECTIVE This pharmacokinetic study of S-1 was conducted in patients in whom glomerular filtration rate (GFR) was directly measured to explore the possibility of adjusting the S-1 dose on the basis of GFR in patients with normal or nearly normal renal function. METHODS S-1 was given to 12 patients twice daily for 28 consecutive days followed by 14 days… CONTINUE READING