Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.

@article{Cabrales2013PharmacokineticSO,
  title={Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.},
  author={Ania Cabrales and Jeovanis Gil and Eduardo Fern{\'a}ndez and Carmen Valenzuela and Francisco Javier Cabrera Hern{\'a}ndez and Idrian Garc{\'i}a Garc{\'i}a and Ariadna Hern{\'a}ndez and Vladimir Besada and Osvaldo Reyes and Gabriel Padron and Jorge Berlanga and Gerardo Guill{\'e}n and Luis Javier Gonz{\'a}lez},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  year={2013},
  volume={48 1-2},
  pages={40-6}
}
GHRP-6 is a growth hormone secretagogue that also enhances tissue viability in different organs. In the present work, we studied the pharmacokinetics of this short therapeutic hexapeptide (His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH(2,) MW=872.44 Da) in nine male healthy volunteers after a single intravenous bolus administration of 100, 200 and 400 μg/kg of body weight. GHRP-6 was quantified in human plasma by a specific LC-MS method, previously developed and validated following FDA guidelines, using… CONTINUE READING

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