Pharmacokinetic-pharmacodynamic relationship of arbekacin for treatment of patients infected with methicillin-resistant Staphylococcus aureus.

@article{Sato2006PharmacokineticpharmacodynamicRO,
  title={Pharmacokinetic-pharmacodynamic relationship of arbekacin for treatment of patients infected with methicillin-resistant Staphylococcus aureus.},
  author={Reiko Sato and Yusuke Tanigawara and Mitsuo Kaku and Naoki Aikawa and Kihachiro Shimizu},
  journal={Antimicrobial agents and chemotherapy},
  year={2006},
  volume={50 11},
  pages={
          3763-9
        }
}
  • Reiko Sato, Yusuke Tanigawara, +2 authors Kihachiro Shimizu
  • Published in
    Antimicrobial agents and…
    2006
  • Medicine
  • Arbekacin is widely used in Japan for the treatment of patients infected with methicillin-resistant Staphylococcus aureus (MRSA). In this study, we have determined the optimal concentration targets of arbekacin for both efficacy and safety. A pharmacokinetic-pharmacodynamic analysis was performed to relate exposure to the drug and clinical cure/improvement or nephrotoxicity. Since we have reported the population pharmacokinetic parameters for arbekacin in the preceding paper (Y. Tanigawara, R… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 17 CITATIONS

    Rapid quantification of the aminoglycoside arbekacin in serum using high performance liquid chromatography-tandem mass spectrometry.

    VIEW 5 EXCERPTS
    CITES METHODS & BACKGROUND
    HIGHLY INFLUENCED

    Clinical Usefulness of Arbekacin

    VIEW 2 EXCERPTS