Pharmacokinetic optimisation of therapy with newer antidepressants.

@article{Goodnick1994PharmacokineticOO,
  title={Pharmacokinetic optimisation of therapy with newer antidepressants.},
  author={Paul J Goodnick},
  journal={Clinical pharmacokinetics},
  year={1994},
  volume={27 4},
  pages={307-30}
}
Since the early 1950s, when imipramine was first introduced, a whole series of antidepressants with differences in structures, neurochemical effects and pharmacokinetics have been developed. Structurally or functionally, they have been classified as tricyclic antidepressants (TCAs), tetracyclic antidepressants, monoamine oxidase inhibitors (MAOIs), or selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs). In addition, there is a series of antidepressants with unique… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

A positron emission tomography microdosing study with sertraline in healthy volunteers.

International journal of clinical pharmacology and therapeutics • 2012

Similar Papers

Loading similar papers…