Pharmacokinetic issues for antibiotics in the critically ill patient.

@article{Roberts2009PharmacokineticIF,
  title={Pharmacokinetic issues for antibiotics in the critically ill patient.},
  author={Jason A. Roberts and Jeffrey Lipman},
  journal={Critical care medicine},
  year={2009},
  volume={37 3},
  pages={840-51; quiz 859}
}
OBJECTIVE To discuss the altered pharmacokinetic properties of selected antibiotics in critically ill patients and to develop basic dose adjustment principles for this patient population. DATA SOURCES PubMed, EMBASE, and the Cochrane-Controlled Trial Register. STUDY SELECTION Relevant papers that reported pharmacokinetics of selected antibiotic classes in critically ill patients and antibiotic pharmacodynamic properties were reviewed. Antibiotics and/or antibiotic classes reviewed included… CONTINUE READING