Corpus ID: 55231532

Pharmacokinetic interaction studies between breast cancer resistance protein (BCRP) inhibiting flavonoids and ciprofloxacin in rats

@inproceedings{Devi2010PharmacokineticIS,
  title={Pharmacokinetic interaction studies between breast cancer resistance protein (BCRP) inhibiting flavonoids and ciprofloxacin in rats},
  author={K. K. Devi},
  year={2010}
}
Pharmacokinetic interaction between ciprofloxacin, an antibacterial fluoroquinolone that was described as a substrate for breast cancer resistance protein (BCRP) and BCRP inhibiting flavonoids curcumin and quercetin in rats was investigated in the present study. Male Wistar albino rats, weighing about 200-250g were randomly divided into three groups consisting six rats in each group. Rats in group I (control) received ciprofloxacin alone (10 mg.kg -1 PO). Group II received curcumin (400 mg.kg… Expand