Pharmacokinetic interaction between oltipraz and silymarin in rats.

@article{Kang2009PharmacokineticIB,
  title={Pharmacokinetic interaction between oltipraz and silymarin in rats.},
  author={Min Kyung Kang and Soo Hyeon Bae and Jin Wan Kim and Myung Gull Lee},
  journal={Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques},
  year={2009},
  volume={12 1},
  pages={1-16}
}
PURPOSE To evaluate the pharmacokinetic interaction between oltipraz and silymarin after intravenous and oral administration of both drugs to male Sprague-Dawley rats. METHODS Oltipraz (single doses of 10 and 30 mg/kg for intravenous and oral administration, respectively), silymarin (single doses of 50 and 100 mg/kg for intravenous and oral administration… CONTINUE READING