Pharmacokinetic evaluation of vortioxetine for the treatment of major depressive disorder

  title={Pharmacokinetic evaluation of vortioxetine for the treatment of major depressive disorder},
  author={Steven L. Dubovsky},
  journal={Expert Opinion on Drug Metabolism \& Toxicology},
  pages={759 - 766}
  • S. Dubovsky
  • Published 9 April 2014
  • Psychology
  • Expert Opinion on Drug Metabolism & Toxicology
Introduction: Major depressive disorder (MDD), one of the most common disorders in medical practice and one of the leading causes of disability worldwide, is frequently comorbid with anxiety disorders. Vortioxetine (Lu AA21004) is a new antidepressant that combines a number of neurotransmitter reuptake and receptor effects that have been thought to predict efficacy as a treatment for depressive and anxiety disorders. Areas covered: This review summarizes the pharmacology and neurobiology of… 

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