Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions.

Abstract

Standard antituberculosis (anti-TB) therapy requires the use of multiple drugs for a minimum of 6 months, with variable outcomes that are influenced by a number of microbiological, pathological, and clinical factors. This is despite the availability of antibiotics that have good activity against Mycobacterium tuberculosis in vitro and favorable… (More)
DOI: 10.1128/AAC.05208-11

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