Pharmacokinetic evaluation of piperacillin-tazobactam

@article{Hayashi2010PharmacokineticEO,
  title={Pharmacokinetic evaluation of piperacillin-tazobactam},
  author={Yoshiro Hayashi and Jason Alexander Roberts and David L. Paterson and Jeffrey Lipman},
  journal={Expert Opinion on Drug Metabolism \& Toxicology},
  year={2010},
  volume={6},
  pages={1017 - 1031}
}
Importance of the field: Piperacillin-tazobactam is a frequently prescribed intravenous antibiotic for moderate to severe infections used in hospital settings because of its broad activity against many pathogenic bacteria including Pseudomonas aeruginosa. However, its pharmacokinetics (PK) can be significantly altered in a variety of states. Areas covered in this review: This article provides a comprehensive and critical review of the PK of piperacillin-tazobactam in different patient… 

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