Pharmacokinetic comparison of beclomethasone dipropionate extrafine aerosol from two inhaler devices in children with asthma

@article{Harrison2002PharmacokineticCO,
  title={Pharmacokinetic comparison of beclomethasone dipropionate extrafine aerosol from two inhaler devices in children with asthma},
  author={Lester I Harrison and Sarala Kurup and Lin-Zhi Chen and Bruce P. Ekholm and Timothy G. Wighton and Gail G. Shapiro},
  journal={European Journal of Clinical Pharmacology},
  year={2002},
  volume={58},
  pages={191-195}
}
Objective. The primary objective was to test the comparability of the pharmacokinetics of beclomethasone dipropionate (BDP) delivered from a pressurized extrafine solution formulation in two inhalation devices in children with asthma. One inhaler was actuated using the press and breathe (P&B) technique and the other was breath-actuated (AH); both inhalers used HFA-134a as propellant. Methods. Eighteen children aged between 9 years and 12 years entered and completed the study; written informed… CONTINUE READING

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