Pharmacokinetic and pharmacological studies with tolamolol in man.

  title={Pharmacokinetic and pharmacological studies with tolamolol in man.},
  author={J. K. Faulkner and D. A. Stopher and Ramsey Walden},
  journal={British journal of clinical pharmacology},
  volume={2 5},
Pharmacokinetic and physiological variables were measured in six healthy subjects after intravenous and oral administration of tolamolol. 2. After intravenous injection of tolamolol (20 mg), there was a biphasic decline both in plasma concentration and attenuation of maximum exercise tachycardia. First and second phase half-lives of plasma concentration… CONTINUE READING