Pharmacokinetic Studies of Chinese Medicinal Herbs Using an Automated Blood Sampling System and Liquid Chromatography-mass Spectrometry

@inproceedings{Wu2012PharmacokineticSO,
  title={Pharmacokinetic Studies of Chinese Medicinal Herbs Using an Automated Blood Sampling System and Liquid Chromatography-mass Spectrometry},
  author={Yu-Tse Wu and Ming-tsang Wu and Chia-chun Lin and Chao-Feng Chien and Tung-Hu Tsai},
  booktitle={Journal of traditional and complementary medicine},
  year={2012}
}
The safety of herbal products is one of the major concerns for the modernization of traditional Chinese medicine, and pharmacokinetic data of medicinal herbs guide us to design the rational use of the herbal formula. This article reviews the advantages of the automated blood sampling (ABS) systems for pharmacokinetic studies. In addition, three commonly used sample preparative methods, protein precipitation, liquid-liquid extraction and solid-phase extraction, are introduced. Furthermore, the… CONTINUE READING
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