Pharmacokinetic Optimisation in the Treatment of Gastro-Oesophageal Reflux Disease

@article{Hatlebakk1996PharmacokineticOI,
  title={Pharmacokinetic Optimisation in the Treatment of Gastro-Oesophageal Reflux Disease},
  author={Jan Gunnar Hatlebakk and Arnold Berstad},
  journal={Clinical Pharmacokinetics},
  year={1996},
  volume={31},
  pages={386-406}
}
SummaryGastro-oesophageal reflux disease (GORD) is a very common disorder of upper gastro-intestinal motility, differing widely in severity and prognosis. Medical therapy of GORD has involved antacids, alginates, prokinetic agents and antisecretory compounds, primarily H2 receptor antagonists and proton pump inhibitors. Knowledge of the pharmacokinetics of these compounds is important, to optimise the therapeutic benefit in each patient.GORD patients are often elderly and pharmacokinetics are… CONTINUE READING
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