Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements.

  title={Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements.},
  author={Alyssa A Sprouse and Richard B van Breemen},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  volume={44 2},
The use of botanical dietary supplements has grown steadily over the last 20 years despite incomplete information regarding active constituents, mechanisms of action, efficacy, and safety. An important but underinvestigated safety concern is the potential for popular botanical dietary supplements to interfere with the absorption, transport, and/or metabolism of pharmaceutical agents. Clinical trials of drug-botanical interactions are the gold standard and are usually carried out only when… CONTINUE READING
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