Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22.

  title={Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22.},
  author={Mingliang Lin and Beverly Ellis and Lisa M. Eubanks and Kim D. Janda},
  journal={ACS chemical neuroscience},
Synthetic cannabinoids are part of a group of drugs called new psychoactive substances. Most of these cannabinoids are unregulated, and there are no therapeutic treatments for their addictive properties or reversing a potential overdose. Vaccination and catalytic antibodies strategies were investigated to assess their ability to blunt the psychoactive properties of the cannabinoid PB-22. To complement these antibody concentric investigations, we also disclose the discovery of the enzymatic… 


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