Pharmacogenomics of hepatitis C infections: personalizing therapy

  title={Pharmacogenomics of hepatitis C infections: personalizing therapy},
  author={David M. Booth and Golo Ahlenstiel and Jacob George},
  booktitle={Genome Medicine},
It is a widely held view that drug response genes have not proved as useful in clinical practice as anticipated at the start of the genomic era. An exception is in the treatment for chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interferon α and ribavirin. In 2009, four independent genome-wide analyses identified IL28B polymorphisms… CONTINUE READING