Pharmacogenomics in diabetes mellitus: insights into drug action and drug discovery

Abstract

Genomic studies have greatly advanced our understanding of the multifactorial aetiology of type 2 diabetes mellitus (T2DM) as well as the multiple subtypes of monogenic diabetes mellitus. In this Review, we discuss the existing pharmacogenetic evidence in both monogenic diabetes mellitus and T2DM. We highlight mechanistic insights from the study of adverse… (More)
DOI: 10.1038/nrendo.2016.51

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