Pharmacogenomics: the importance of accurate phenotypes.

  title={Pharmacogenomics: the importance of accurate phenotypes.},
  author={David Gurwitz and Munir Pirmohamed},
  volume={11 4},
Lack of knowledge regarding genotype-phenotype correlations is often cited as the major barrier delaying the uptake of pharmacogenomics into routine medical practice. When we look forward to genome-wide association studies as one of the most promising tools for overcoming the pharmacogenomics knowledge barrier, we must keep in mind that having large patient cohorts may not help improve our understanding of alleles implicated in drug-response phenotypes, unless we ensure that such phenotypes are… CONTINUE READING


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Big Data Analytics for Genomic Medicine

International journal of molecular sciences • 2017


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