Pharmacogenetics predictors of methylphenidate efficacy in childhood ADHD

  title={Pharmacogenetics predictors of methylphenidate efficacy in childhood ADHD},
  author={Nicole Myer and J R Boland and Stephen V Faraone},
  journal={Molecular Psychiatry},
Stimulant medication has long been effective in treating attention-deficit/hyperactivity disorder (ADHD) and is currently the first-line pharmacological treatment for children. Both methylphenidate and amphetamine modulate extracellular catecholamine levels through interaction with dopaminergic, adrenergic and serotonergic system components; it is therefore likely that catecholaminergic molecular components influence the effects of ADHD treatment. Using meta-analysis, we sought to identify… CONTINUE READING


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