Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: association with the dopamine transporter gene (SLC6A3).

@article{PurperOuakil2008PharmacogeneticsOM,
  title={Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: association with the dopamine transporter gene (SLC6A3).},
  author={Diane Purper-Ouakil and Mathias Wohl and Silvia Orejarena and Samuele Cortese and Claudette Boni and Muriel Asch and Marie Christine Mouren and Philip Gorwood},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2008},
  volume={147B 8},
  pages={1425-30}
}
Pharmacogenetic studies investigating the 40-bp VNTR polymorphism at SLC6A3 and methylphenidate response have shown conflicting results and large differences in study design and efficacy endpoints. Our objective was to investigate the relation between the 3'-VNTR at SLC6A3 and variability in methylphenidate response in a sample of 141 ADHD children and… CONTINUE READING