Pharmacogenetics of antipsychotic-induced side effects

  title={Pharmacogenetics of antipsychotic-induced side effects},
  author={Todd Lencz and Anil K. Malhotra},
  booktitle={Dialogues in clinical neuroscience},
Currently available antipsychotic drugs (APDs) carry significant though highly variable, liability to neurologic and metabolic side effects. Pharmacogenetics approaches offer the possibility of identifying patient-specific biomarkers for predicting risk of these side effects. To date, a few single nucleotide polymorphisms (SNPs) in a handful of genes have received convergent support across multiple studies. The primary focus has been on SNPs in dopamine and serotonin receptor genes: persuasive… CONTINUE READING