Pharmacogenetics of antidepressive treatment

  title={Pharmacogenetics of antidepressive treatment},
  author={Astrid W. Zobel and Wolfgang Maier},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  • A. Zobel, W. Maier
  • Published 3 January 2010
  • Biology, Psychology, Medicine
  • European Archives of Psychiatry and Clinical Neuroscience
The search of the genetic predictors of response to antidepressants is a rapidly expanding field. A large number of clinical studies are reporting partly inconsistent results. Emerging new results focus on new candidate single nucleotide polymorphisms—particularly in the 5HT2a-receptor gene and the gene coding for the co-chaperone FKBP5. The impact of the 5HTTLPR polymorphism on therapeutic outcome and side effects under treatment with SSRIs has to be viewed in a more complex manner than… 

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    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
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