Pharmacogenetics in Africa, an Opportunity for Appropriate Drug Dosage Regimens: on the Road to Personalized Healthcare

@inproceedings{Masimirembwa2013PharmacogeneticsIA,
  title={Pharmacogenetics in Africa, an Opportunity for Appropriate Drug Dosage Regimens: on the Road to Personalized Healthcare},
  author={Collen Masimirembwa and Julia Anne Hasler},
  year={2013}
}
Approximately 60 years ago, the metabolism and disposition of isoniazid, an antituberculosis drug, was one of the earliest demonstrations of pharmacogenetic differences in drug handling that resulted in clinical consequences.2 There were marked differences in excretion of the drug among individuals who were then classified into slow acetylators (SA) and… CONTINUE READING