Pharmacogenetics: from bench to byte--an update of guidelines.

  title={Pharmacogenetics: from bench to byte--an update of guidelines.},
  author={J. J. Swen and Marga Nijenhuis and Angela G. E. M. de Boer and Larry Grandia and Anke-Hilse Maitland-van der Zee and H. V. Mulder and Gerard A P J M Rongen and Ron H. N. van Schaik and Tom Schalekamp and Daan Johannes Touw and J A M Van Der Weide and Bob Wilffert and Vera H M Deneer and H. Guchelaar},
  journal={Clinical pharmacology and therapeutics},
  volume={89 5},
Currently, there are very few guidelines linking the results of pharmacogenetic tests to specific therapeutic recommendations. Therefore, the Royal Dutch Association for the Advancement of Pharmacy established the Pharmacogenetics Working Group with the objective of developing pharmacogenetics-based therapeutic (dose) recommendations. After systematic review of the literature, recommendations were developed for 53 drugs associated with genes coding for CYP2D6, CYP2C19, CYP2C9, thiopurine-S… CONTINUE READING
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