Pharmacogenetics: From Bench to Byte— An Update of Guidelines

  title={Pharmacogenetics: From Bench to Byte— An Update of Guidelines},
  author={J. Swen and M. Nijenhuis and A. Boer and L. Grandia and A. Maitland‐van der Zee and H. Mulder and G. Rongen and R. Schaik and T. Schalekamp and D. Touw and J. Weide and B. Wilffert and V.H.M. Deneer and H. Guchelaar},
  journal={Clinical Pharmacology & Therapeutics},
  • J. Swen, M. Nijenhuis, +11 authors H. Guchelaar
  • Published 2011
  • Medicine
  • Clinical Pharmacology & Therapeutics
  • Currently, there are very few guidelines linking the results of pharmacogenetic tests to specific therapeutic recommendations. Therefore, the Royal Dutch Association for the Advancement of Pharmacy established the Pharmacogenetics Working Group with the objective of developing pharmacogenetics‐based therapeutic (dose) recommendations. After systematic review of the literature, recommendations were developed for 53 drugs associated with genes coding for CYP2D6, CYP2C19, CYP2C9, thiopurine‐S… CONTINUE READING
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