Pharmacogenetics, pharmacogenomics, and individualized medicine.

  title={Pharmacogenetics, pharmacogenomics, and individualized medicine.},
  author={Qiang Ma and A. Y. Lu},
  journal={Pharmacological reviews},
  volume={63 2},
Individual variability in drug efficacy and drug safety is a major challenge in current clinical practice, drug development, and drug regulation. For more than 5 decades, studies of pharmacogenetics have provided ample examples of causal relations between genotypes and drug response to account for phenotypic variations of clinical importance in drug therapy. The convergence of pharmacogenetics and human genomics in recent years has dramatically accelerated the discovery of new genetic… CONTINUE READING
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The Acetylator Genes and Drug Response

  • WW Weber
  • 1987
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