Pharmacogenetic tests in asthma therapy.

  title={Pharmacogenetic tests in asthma therapy.},
  author={I-Wen Yu and Bonny L. Bukaveckas},
  journal={Clinics in laboratory medicine},
  volume={28 4},
beta2-Agonist medications, such as albuterol and salmeterol, are widely used to treat asthma. However, there are a significant number of poor responders. Poor response may present as decreased lung function, and in extreme cases (a small percentage), patients who have asthma are at increased risk for mortality. A common single nucleotide polymorphism (SNP) in the beta2-adrenergic receptor gene (ADRB2) results in an arginine substitution for glycine at amino acid 16 (Arg16-->Gly) of the beta2… CONTINUE READING


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