Pharmacogenetic investigation of response to duloxetine treatment in generalized anxiety disorder


We examined genetic associations with duloxetine response in generalized anxiety disorder (GAD). Three pooled studies in patients with GAD receiving duloxetine 60–120 mg per day (N=164) or placebo (N=95) were used. Associations between 825 single-nucleotide polymorphisms (SNPs) in 61 candidate genes with change in Hamilton Anxiety Scale scores were examined… (More)
DOI: 10.1038/tpj.2011.62

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